Hesperetin attenuates silica‑induced lung injury by reducing oxidative damage and inflammatory response
نویسندگان
چکیده
منابع مشابه
Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response.
Because therapeutic options are lacking for bronchopulmonary dysplasia (BPD), there is an urgent medical need to discover novel targets/drugs to treat this neonatal chronic lung disease. Metformin, a drug commonly used to lower blood glucose in type 2 diabetes patients, may be a novel therapeutic option for BPD by reducing pulmonary inflammation and fibrosis and improving vascularization. We in...
متن کاملH2S Attenuates LPS-Induced Acute Lung Injury by Reducing Oxidative/Nitrative Stress and Inflammation.
BACKGROUND Hydrogen sulfide (H2S), known as the third endogenous gaseous transmitter, has received increasing attention because of its diverse effects, including angiogenesis, vascular relaxation and myocardial protection.We aimed to investigate the role of H2S in oxidative/nitrative stress and inflammation in acute lung injury (ALI) induced by endotoxemia. METHODS Male ICR mice were divided ...
متن کاملHydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
Molecular hydrogen (H(2)) is an efficient antioxidant that diffuses rapidly across cell membranes, reduces reactive oxygen species (ROS), such as hydroxyl radicals and peroxynitrite, and suppresses oxidative stress-induced injury in several organs. ROS have been implicated in radiation-induced damage to lungs. Because prompt elimination of irradiation-induced ROS should protect lung tissue from...
متن کاملCALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response
Xueyu Chen, Frans J. Walther, Rozemarijn M. A. Sengers, El Houari Laghmani, Asma Salam, Gert Folkerts, Tonio Pera, and Gerry T. M. Wagenaar Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands; Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles Medical Center, Torrance, Calif...
متن کاملBarley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response
It has been reported that barley leaves possess beneficial properties such as antioxidant, hypolipidemic, antidepressant, and antidiabetic. Interestingly, barley sprouts contain a high content of saponarin, which showed both anti-inflammatory and antioxidant activities. In this study, we evaluated the effect of barley sprouts on alcohol-induced liver injury mediated by inflammation and oxidativ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2021
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2021.9728